What’s Next in Istanbul: Vault Karaköy, The House Hotel
This former bank building (hence the name) is the de-facto hangout for business-minded travelers spending some of their time in the emerging neighborhood of Karaköy, but it gets high marks for all the hotel requisites—service, style, amenities—and not just for its cool-kid location. It’s just four tram stops from the Old City, and steps from buzzy destinations like the Unter nightclub, Lokanta Maya, and all the top art galleries. We love the arched windows, crown moldings, and starched white linens in the guest rooms. Bankalar Caddesi No. 5; 90-212/244-6434; thehousehotel.com.