In recent years, this tiny three-block strip has transformed into one of the most exclusive shopping destinations in L.A. Anchored by Marc Jacobs (8400 Melrose Ave.; 323-653-5100; marcjacobs.com) at one end, and Monique Lhuillier (8485 Melrose Pl.; 323-655-1088; moniquelhuillier.com) at the other, the picturesque tree-lined street is filled with can’t-miss boutiques, such as the first flagship for The Row (8440 Melrose Pl.; 310-853-1900; therow.com)—housed in a chic residential-style midcentury gem, complete with a Slims Aarons-esque pool—and the Commune-designed salon of Venice-based jeweler Irene Neuwith (8458 Melrose Pl.; 323-285-2000; ireneneuwirth.com). Other highlights include a brick-and-mortar for ecommerce beauty mecca Violet Grey (8452 Melrose Pl.; 323-782-9700; violetgrey.com) and the west coast outpost of fashion-cum–home decor favorite The Apartment by the Line (8463 Melrose Pl.; 323-746-5056; theline.com).